Resources


Database Credentialed Access

Association of Sleep Electroencephalography-Based Brain Age Index With Dementia - Data and code

Elissa Ye, Haoqi Sun, Michael Leone, Luis Paixao, Robert Thomas, Alice Lam, M Brandon Westover

De-identified polysomnography dataset and analysis code from Ye et al. 2020 (JAMA Netw Open): sleep-EEG-based Brain Age Index (BAI) computed across 9,834 MGH Sleep Lab PSGs and tested as a biomarker for dementia and MCI versus healthy controls.

machine learning biomarker sleep mild cognitive impairment polysomnography dementia eeg brain age

Published: April 25, 2026. Version: 1.0.0

Database Credentialed Access

Dementia detection from brain activity during sleep - data and code

Elissa Ye, Haoqi Sun, Wolfgang Ganglberger, Robert Thomas, Alice Lam, M Brandon Westover

Code and curated polysomnography dataset (10,784 PSGs from 8,044 patients, MGB Sleep Lab 2009-2019) used in Ye et al. 2023 (Sleep) to detect dementia and MCI from sleep EEG features.

machine learning biomarker sleep mild cognitive impairment polysomnography dementia eeg

Published: April 25, 2026. Version: 1.0.0

Database Credentialed Access

ELUCID: Late-Onset Unexplained Epilepsy as a Risk Factor for Cognitive Impairment and Dementia — A Multi-Center Prospective Longitudinal Study (Protocol and Data Resource)

Alice Lam, Emily Johnson, rani sarkis, Leah J. Blank, Tyler E. Gaston, Mouhsin Shafi, Rodrigo Zepeda, Niyatee Samudra, Keith A. Vossel, Ifrah Zawar, Douglas N. Greve, Lori B. Chibnik, Rebecca E. Amariglio, Gad A. Marshall, M. Brandon Westover

ELUCID is a 7-center longitudinal study of 600 adults aged 55+ with late-onset unexplained epilepsy, building a multimodal biorepository (brain MRI, overnight EEG, cognitive testing, blood biomarkers) to identify risk factors for dementia.

Published: July 29, 2026. Version: 1.0.0

Database Open Access

Assessing Risk of Health Outcomes From Brain Activity in Sleep

Haoqi Sun, Noor Adra, Muhammad Ayub, Wolfgang Ganglberger, Elissa Ye, Ziwei Fan, Aditya Gupta, Valdery Moura Junior, M Brandon Westover, Robert Thomas

Using sleep EEG to predict future health outcomes.

Published: Oct. 30, 2025. Version: 1.1