Resources


Database Credentialed Access

Automated detection of immune effector cell-associated neurotoxicity syndrome (ICANS) via quantitative EEG

Christine Eckhardt, Haoqi Sun, Jin Jing, Daniel Rubin, Eyal Kimchi, Sydney Cash, Matthew J. Frigault, Jong Woo Lee, Jorg Dietrich, M Brandon Westover

Dataset and code for developing and validating the EICANS score, a machine learning–derived EEG metric for automated detection and grading of immune effector cell-associated neurotoxicity syndrome (ICANS) in patients receiving CAR-T cell therapy.

car-t encephalopathy neurotoxicity eeg

Published: Feb. 9, 2026. Version: 1.0

Software Credentialed Access

EEG-based grading of immune effector cell-associated neurotoxicity syndrome

Daniel Jones, Christine Eckhardt, Haoqi Sun, Ryan A. Tesh, Preeti Malik, Syed Quadri, Marcos Santana Firme, Meike van Sleuwen, Aayushee Jain, Ziwei Fan, Jin Jing, Wendong Ge, Fábio A. Nascimento, Irfan S. Sheikh, Caron Jacobson, Matthew J. Frigault, Eyal Y. Kimchi, Sydney Cash, Jong Woo Lee, Jorg Dietrich, M. Brandon Westover

An interpretable ordinal EEG-feature score (VE-ICANS) that grades the severity of immune effector cell-associated neurotoxicity syndrome (ICANS) after CAR-T therapy. Code + de-identified data.

Published: July 7, 2026. Version: 1.0.0